Our Advisory Council
To respond to the increasin...
An alliance of prominent or...
An advocacy tool
A contagious diarrhoeal dis...
Our prevention strategy
Methodology for the elimina...
A best practice model in th...
A best practice model in the Democratic Republic of Congo
Cholera Source Areas in DRC
A multisectorial action plan
Logos & banners
democratic republic of the congo
full text open access
african great lakes region
Micro-Hotspots of Risk in Urban Cholera Epidemics
Andrew S Azman | Francisco J Luquero | Henrik Salje | Nathan Naibei Mbaïbardoum | Ngandwe Adalbert | Mohammad Ali | Enrico Bertuzzo | Flavio Finger | Brahima Touré | Louis Albert Massing | Romain Ramazani | Bansaga Saga | Maya Allan | David Olson | Jerome Leglise | Klaudia Porten | Justin Lessler
Date of Publication:
The Journal of Infectious Diseases
Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and Democratic Republic of the Congo, we estimated the extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200 meters during the five days immediately after case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for rapidly delivering targeting interventions.
Highly targeted cholera vaccination campaigns in urban setting are feasible: The experience in Kalemie, Democratic Republic of Congo
Louis Albert Massing | Soumah Aboubakar | Alexandre Blake | Anne-Laure Page | Sandra Cohuet | Adalbert Ngandwe | Eric Mukomena Sompwe | Romain Ramazani | Marcela Allheimen | Philippe Levaillant | Pauline Lechevalier | Marie Kashimi | Axelle de la Motte | Arielle Calmejane | Malika Bouhenia | Ernest Dabire | Didier Bompangue | Benoit Kebela | Klaudia Porten | Francisco Luquero
Date of Publication:
PLoS neglected tropical diseases
The oral cholera vaccine (OCV), Shanchol, has already been shown as an effective tool in controlling cholera outbreaks. The limited amount of doses, concurrently with the logistic constraints associated with a targeted vaccination campaign are serious difficulties to tackle to organize vaccination campaigns in urban settings. Although the World Health Organization recommends its use for cholera control in endemic countries, the fact remains that the use of the OCV in endemic setting has scarcely been described, especially in an urban setting, until now. Médecins Sans Frontières and the Ministry of Health from Democratic Republic of Congo organized a vaccination campaign of a limited part of the urbanized and highly endemic city of Kalemie, in Tanganyika Province, using a door-to-door strategy. The vaccine coverage in the targeted zones was high and demonstrated the feasibility of cholera vaccination campaign in this setting but also the need for creative strategies to reach populations that are hard to vaccine.